Two Cases of Spinal Tanycytic Ependymoma Associated with Neurofibromatosis Type 2

IntroductIon Tanycytic ependymoma is a rare subtype of the World Health Organization Grade II ependymoma most commonly found in the cervical and thoracic segments of the spinal cord. Spinal tumors in neurofibromatosis type 2 (NF‐2) can be intramedullary, extramedullary, or associated with the nerve roots, and there may be multiple tumors at multiple locations in the spine. The histology of these tumors includes meningiomas, schwannomas, ependymomas, and neurofibroma.[1] However, spinal tanycytic ependymomas associated with NF‐2 are extremely rare, with only four cases reported in the English literature.[1‐4] In this study, we report two rare cases of spinal tanycytic ependymoma associated with NF‐2 and provide a review of the literature.